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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Neuroprotection in early stages of Alzheimer’s disease is promoted by transthyretin angiogenic properties

Fig. 4

Effect of TTR reduction on collagen IV levels, in NT and AD mice. Representative images and quantification plots of collagen IV (red) immunostaining depicting microvessels of NT/TTR+/− (n = 4) and AD/TTR+/− (n = 5) 3-month-old mice in cortex and hippocampus, showing an increase in collagen IV expression in AD/TTR+/− mice relatively to NT/TTR+/− littermates, in the hippocampus. Data are expressed as mean ± SEM. *p < 0.05. Scale bar = 5 μm

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