Fig. 2

Multi-spectral occipital dynamics in patients on the Alzheimer’s disease spectrum. Spectrograms on the far left are representative sensors displaying the significant time–frequency responses identified in the sensor-level analysis, with percent change from baseline indicated on the scale bar above. Large brain maps in the middle represent occipital neural responses per each frequency band (top: theta; middle: alpha; bottom: gamma) that have been grand averaged over all participants. Smaller maps in the middle show these same responses averaged within each group (top: cognitively normal [CN] controls; bottom: Alzheimer’s disease spectrum [ADS]). Peak voxel virtual sensor time series per group are displayed on the right for these responses (averaged across hemispheres per group), with the gray shaded areas indicating time windows identified in the sensor-level analysis and imaged using a beamformer, and the colored shaded areas indicating ± 1 standard error of the mean