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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Tau-PET and in vivo Braak-staging as prognostic markers of future cognitive decline in cognitively normal to demented individuals

Fig. 3

Tau-PET-based Braak-staging versus annual cognitive change rates for the Mini-Mental State Examination (MMSE; A), the Alzheimer’s Disease Assessment Scale Cognition 13-item scale (ADAS13; B), and the ADNI-MEM score (C). Statistics were derived from ANCOVA models controlling for age, sex, education, clinical diagnosis, global amyloid-PET (Centiloid), and the baseline score of the respective cognitive test. Post hoc Tukey tests were used in order to determine differences in cognitive changes between Braak-stage groups; ** = p < 0.01, *** = p < 0.001

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