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Table 2 Demographic data, cognitive test scores, and the number of ApoE ε4 alleles of the selected AIBL subjects separated by diagnosis group

From: Data analysis with Shapley values for automatic subject selection in Alzheimer’s disease data sets using interpretable machine learning

Variable sMCI pMCI Σ p value
n 16 12 28  
Age (in years) 77.8 ±6.9 75.3 ±5.8 76.8 ±6.5 0.2856
Gender (proportion of females) 37.5% 33.3% 35.7% 1.0000
Gender (proportion of males) 62.5% 66.7% 64.3%  
MMSE 28.0 ±1.7 26.3 ±1.6 27.3 ±1.8 0.0133
CDR 0.4 ±0.2 0.5 ±0.0 0.5 ±0.1 0.2317
ApoE ε4 (proportion of subjects with 0 alleles) 56.3% 16.7% 39.3% 0.0550
ApoE ε4 (proportion of subjects with 1 allele) 37.5% 50.0% 42.9%  
ApoE ε4 (proportion of subjects with 2 alleles) 6.3% 33.3% 17.9%  
Time to final diagnosis in months 41.3 ±22.4 28.4 ±14.2 35.7 ±20.1 <0.2457
  1. For continuous features, mean and standard deviation are given. p values are calculated using Mann-Whitney U test [49, 50] for continuous features and using χ2-test for ordinal and nominal features