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Table 2 Demographic data, cognitive test scores, and the number of ApoE ε4 alleles of the selected AIBL subjects separated by diagnosis group

From: Data analysis with Shapley values for automatic subject selection in Alzheimer’s disease data sets using interpretable machine learning

Variable

sMCI

pMCI

Σ

p value

n

16

12

28

 

Age (in years)

77.8 ±6.9

75.3 ±5.8

76.8 ±6.5

0.2856

Gender (proportion of females)

37.5%

33.3%

35.7%

1.0000

Gender (proportion of males)

62.5%

66.7%

64.3%

 

MMSE

28.0 ±1.7

26.3 ±1.6

27.3 ±1.8

0.0133

CDR

0.4 ±0.2

0.5 ±0.0

0.5 ±0.1

0.2317

ApoE ε4 (proportion of subjects with 0 alleles)

56.3%

16.7%

39.3%

0.0550

ApoE ε4 (proportion of subjects with 1 allele)

37.5%

50.0%

42.9%

 

ApoE ε4 (proportion of subjects with 2 alleles)

6.3%

33.3%

17.9%

 

Time to final diagnosis in months

41.3 ±22.4

28.4 ±14.2

35.7 ±20.1

<0.2457

  1. For continuous features, mean and standard deviation are given. p values are calculated using Mann-Whitney U test [49, 50] for continuous features and using χ2-test for ordinal and nominal features