BG-ePVS | CS-ePVS | ||||||||
---|---|---|---|---|---|---|---|---|---|
N | Mean (SD) or n (%) | Degree 1 (n = 162) | Degree 2 + Degree 3 (n = 160) | p value | Degree 1 (n = 90) | Degree 2 (n = 147) | Degree 3 + 4 (n = 85) | p value | |
Sex, n (%) | 322 | 0.156 | 0.549 | ||||||
Male | 118 (36.6%) | 66 (40.7%) | 52 (32.5%) | 35 (38.9%) | 56 (38.1%) | 27 (31.8%) | |||
Female | 204 (63.4%) | 96 (59.3%) | 108 (67.5%) | 55 (61.1%) | 91 (61.9%) | 58 (68.2%) | |||
Age (years) | 322 | 60.7 (4.69) | 59.4 (4.67) | 62.0 (4.37) | < 0.001 | 59.8 (4.76) | 60.5 (4.62) | 62.0 (4.50) | 0.006 |
APOE-ε4 allele status, n (%) | 322 | 0.182 | 0.643 | ||||||
Non-carriers | 156 (48.4%) | 72 (44.4%) | 84 (52.5%) | 43 (47.8%) | 75 (51.0%) | 38 (44.7%) | |||
Carriers | 166 (51.6%) | 90 (55.6%) | 76 (47.5%) | 47 (52.2%) | 72 (49.0%) | 47 (55.3%) | |||
Education (years) | 318 | 13.4 (3.50) | 13.6 (3.39) | 13.2 (3.61) | 0.346 | 13.3 (3.22) | 13.8 (3.50) | 12.9 (3.76) | 0.188 |
Diabetes, n (%) | 304 | 0.531 | 0.161 | ||||||
No | 294 (96.7%) | 141 (95.9%) | 153 (97.5%) | 77 (93.9%) | 137 (98.6%) | 80 (96.4%) | |||
Yes | 10 (3.29%) | 6 (4.08%) | 4 (2.55%) | 5 (6.10%) | 2 (1.44%) | 3 (3.61%) | |||
Dyslipidemia, n (%) | 304 | 0.406 | 0.551 | ||||||
No | 159 (52.3%) | 81 (55.1%) | 78 (49.7%) | 47 (57.3%) | 71 (51.1%) | 41 (49.4%) | |||
Yes | 145 (47.7%) | 66 (44.9%) | 79 (50.3%) | 35 (42.7%) | 68 (48.9%) | 42 (50.6%) | |||
BMI (kg/m2) | 322 | 27.0 (4.16) | 27.5 (4.34) | 26.4 (3.91) | 0.014 | 27.8 (4.64) | 26.8 (3.72) | 26.5 (4.27) | 0.077 |
Systolic Blood Pressure (mmHg) | 321 | 133 (15.9) | 131 (14.9) | 135 (16.4) | 0.007 | 131 (14.9) | 133 (15.2) | 135 (17.7) | 0.228 |
Diastolic Blood Pressure(mmHg) | 321 | 75.4 (9.89) | 75.7 (9.56) | 75.1 (10.2) | 0.541 | 74.1 (9.80) | 75.1 (9.80) | 77.2 (9.97) | 0.100 |
Cholesterol (mg/dL) | 292 | 204 (30.8) | 204 (29.1) | 204 (32.4) | 0.871 | 205 (32.3) | 203 (32.1) | 203 (27.2) | 0.886 |
Physical Activity, n (%) | 288 | 0.089 | 0.326 | ||||||
Non-active | 55 (19.1%) | 20 (14.6%) | 35 (23.2%) | 12 (15.8%) | 24 (17.8%) | 19 (24.7%) | |||
Active | 233 (80.9%) | 117 (85.4%) | 116 (76.8%) | 64 (84.2%) | 111 (82.2%) | 58 (75.3%) | |||
CAIDE score (0–15) | 286 | 6.00 [4.00;7.00] | 5.00 [4.00;7.00] | 6.00 [4.00;7.00] | 0.129 | 5.00 [4.00;7.00] | 5.00 [4.00;6.00] | 6.00 [4.75;7.00] | 0.089 |
Total GM (mm3) | 278 | 588,244 (49,789) | 597,109 (47,771) | 580,229 (50,376) | 0.004 | 584,964 (48,140) | 590,616 (50,255) | 587,617 (51,210) | 0.726 |
WMH (ml) | 257 | 3.33 (16.6) | 1.43 (1.72) | 5.08 (22.9) | 0.068 | 1.39 (1.39) | 4.83 (23.7) | 2.48 (2.84) | 0.346 |
TIV (mm3) | 278 | 1,438,565 (171,034) | 1,456,206 (166,776) | 1,422,616 (173,823) | 0.101 | 1,427,412 (163,677) | 1,442,693 (179,156) | 1,443,534 (165,757) | 0.792 |