Skip to main content

Table 2 Summary of global network measures

From: Tau-related grey matter network breakdown across the Alzheimer’s disease continuum

  Control
n = 178
Preclinical AD
n = 105
Prodromal AD
n = 122
AD dementia
n =128
Network size 7171.15 (671.92)d 7007.46 (672.18)d 6987.52 (612.17)d 6666.01 (581.66)a, b, c
Degree 1193.11 (148.21) d 1159.10 (139.57)d 1140.61 (133.61)d 1072.01 (138.78)a, b, c
Connectivity density 16.61 (0.98) 16.53 (1.07) 16.30 (0.92) 16.06 (1.27)
Clustering coefficient 0.46 (0.02)c, d 0.46 (0.02)c, d 0.45 (0.02)a, b, d 0.44 (0.02)a, b, c
Path length 1.98 (0.03)c, d 1.97 (0.03)c, d 1.96 (0.03)a, b, d 1.96 (0.03)a, b, c
Gamma 1.58 (0.11)c, d 1.54 (0.12)c, d 1.50 (0.09)a, b, d 1.43 (0.09)a, b, c
Lambda 1.08 (0.01)c, d 1.08 (0.02)c, d 1.07 (0.01)a, b, d 1.06 (0.01)a, b, c
Small world coefficient 1.47 (0.08)c, d 1.43 (0.09)c, d 1.40 (0.07)a, b, d 1.35 (0.07)a, b, c
  1. Data are presented as mean ± SD; AD Alzheimer’s disease; gamma is normalised clustering; lambda is normalised path length; asignificantly different than control; bsignificantly different than preclinical AD; csignificantly different than prodromal AD; dsignificantly different than AD dementia at p < 0.05 when adjusting for age, sex, TIV, and connectivity density (clustering, path length, γ, λ, small world-only)