Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer’s disease in Caribbean Hispanics

Table 4 Significant cis expression quantitative loci (eQTLs) for candidate genes within 3q13.11 region of interest

Position	SNP	Gene	Z	β	Allele	P	FDR
105,108,867	rs6797043	ALCAM	-4.89	-0.3429	C	1.29E-06	8.24E-05
107,583,197	rs9875001	BBX	3.72	0.2620	T	2.17E-04	7.43E-03
105,488,134	rs139969708	CBLB	4.01	0.4411	T	7.03E-05	2.85E-03
107,550,819	rs1908324	CD47	3.83	0.2512	T	1.45E-04	5.29E-03
107,917,824	rs9857584	IFT57	6.91	0.6714	C	1.33E-11	1.89E-09
107,823,224	rs80003826	MYH15	-3.92	-0.4498	A	9.85E-05	3.80E-03

Results are filtered to only include those with false discovery rate (FDR) < 0.05, restricted to the SNP with the smallest FDR value. Results for all significant eQTLs are presented in Additional file 8 and the original data can be found at https://www.synapse.org/#!Synapse:syn17015233. Legend: Position = GRCh37 position of the variant on chromosome 3, Z = Z statistic, β = estimated effect size, allele = effect allele, FDR = false discovery rate

ISSN: 1758-9193