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Table 3 Variants with significant or suggestive evidence for association with Alzheimer’s disease within 3q13.11

From: Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer’s disease in Caribbean Hispanics

Chr

SNP

Position

Allele

Gene

Consequence

OR (95% CI)

P

3

rs1731642

103,811,750

G

38kb 5' of AC016970.1

intergenic

1.33 (1.17—1.53)

6.36E05

3

rs9848147

104,111,719

C

338kb 5' of AC016970.1

intergenic

1.65 (1.302.08)

7.02E−05

3

rs2673478

104,158,244

G

385kb 5' of AC016970.1

intergenic

1.22 (1.091.38)

1.33E−03

3

rs16850638

104,594,467

A

491kb 5' of ALCAM

intergenic

0.69 (0.570.84)

4.24E−04

3

rs12492893

104,667,061

A

419kb 5' of ALCAM

intergenic

1.23 (1.101.38)

5.45E−04

3

rs9288795

104,683,753

G

402kb 5' of ALCAM

intergenic

0.83 (0.740.92)

1.21E−03

3

rs16850772

104,736,837

A

349kb 5' of ALCAM

intergenic

1.26 (1.121.41)

1.91E−04

3

rs9883825

104,745,091

G

341kb 5' of ALCAM

intergenic

0.80 (0.710.90)

3.55E−04

3

rs13325696

104,755,481

A

330kb 5' of ALCAM

intergenic

1.28 (1.131.45)

2.29E−04

3

rs1503079

104,759,032

A

327kb 5' of ALCAM

intergenic

0.81 (0.720.91)

4.92E−04

3

rs1566720

104,761,408

A

324kb 5' of ALCAM

intergenic

0.82 (0.730.92)

1.13E−03

3

rs1587707

104,786,133

C

300kb 5' of ALCAM

intergenic

0.80 (0.710.89)

2.06E−04

3

rs2895295

104,790,415

C

295kb 5' of ALCAM

intergenic

0.80 (0.710.90)

2.32E−04

3

rs10933809

104,800,350

A

285kb 5' of ALCAM

intergenic

0.79 (0.700.89)

1.19E−04

3

rs1503089

104,805,417

G

280kb 5' of ALCAM

intergenic

1.23 (1.091.39)

9.28E−04

3

rs1503075

104,806,853

G

279kb 5' of ALCAM

intergenic

0.81 (0.720.92)

1.23E−03

3

rs1503158

104,815,105

G

271kb 5' of ALCAM

intergenic

0.80 (0.710.90)

5.52E−04

3

rs13322578

105,002,637

A

83kb 5' of ALCAM

intergenic

0.77 (0.660.89)

5.90E−04

3

rs9816851

105,012,805

G

73kb 5' of ALCAM

intergenic

0.77 (0.670.89)

6.64E−04

3

rs9860520

106,416,700

A

9.1kb 3' of Y_RNA

intergenic

0.79 (0.700.90)

4.28E−4

3

rs12489299

106,985,680

A

DUBR

intron

0.69 (0.570.83)

1.70E−04

3

rs12494162

107,036,379

A

DUBR

Intron

0.69 (0.60—0.80)

2.33E06

3

rs7615167

107,514,134

A

BBX

Intron

1.56 (1.202.02)

1.23E−03

3

rs4855772

107,540,375

G

10kb 3' of BBX

intergenic

1.80 (1.312.49)

5.81E−04

  1. Significance thresholds are based on the effective number of independent tests. Abbreviations: Chr = chromosome, SNP = single-nucleotide polymorphism identifier, Position = chromosome 3 position on the GRCh37/hg19 map, Allele = effect allele, OR = odds ratio, significant evidence of association = P < 6.7E-05, suggestive evidence of association = P < 1.4E-03. Significant results are highlighted in bold font