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Table 1 Aβ groups definitions

From: Cognitively unimpaired individuals with a low burden of Aβ pathology have a distinct CSF biomarker profile



Low burden


Definition 1

CSF- and CL < 30

CSF+ and CL < 30

CSF+ and CL > 30

Definition 2

CSF- and VR-

CSF+ and VR-

CSF+ and VR+

Definition 3

CL < 20

20–40 CL

CL > 40

  1. “Low burden” refers to “low burden of Aβ pathology”. Abbreviations: amyloid-β, CL Centiloid, CSF cerebrospinal fluid, VR visual read