Table 1 Demographics characteristics and group comparisons
From: Pathological correlates of impaired self-awareness of memory function in Alzheimer’s disease
All | Normal | Impaired | Clinical groups | ||||
|---|---|---|---|---|---|---|---|
A− | A+ | A− | A+ | Normal | Impaired | ||
N | 338 | 151 | 85 | 50 | 52 | 236 | 102 |
Age | 71.42 (6.53) | 69.94 (5.64) | 73.11 (6.59) a** | 71.53 (7.78) | 72.88 (6.69) a* | 71.08 (6.18) | 72.21 (7.25) |
Gender | 174F (51.48%) | 88F (58.28%) | 47F (55.29%) | 17F (34%) a** | 22F (42.31%) | 135F (57.2%) | 39F (38.24%) c** |
Education (years of study) | 16.69 (2.61) | 16.97 (2.48) | 16.79 (2.39) | 15.98 (3.09) | 16.4 (2.72) | 16.91 (2.44) | 16.2 (2.9) |
APOE4 status (E4) | 66 (19.53%) | 18 (11.92%) | 25 (29.41%) a** | 8 (16%) | 15 (28.85%) a**, b* | 43 (18.22%) | 23 (22.55%) c* |
MMSE | 28.81 (1.41) | 29.25 (1.08) | 28.68 (1.44) a** | 28.48 (1.42) a** | 28.06 (1.76) a** | 29.04 (1.25) | 28.26 (1.61) c** |
GDS | 1.4 (1.85) | 1.14 (1.74) | 1.04 (1.19) | 1.74 (2.19) | 2.14 (2.27) | 1.1 (1.54) | 1.93 (2.22) c* |
Logical Memory (delayed) | 12.51 (4.8) | 13.85 (3.88) | 14.33 (3.7) | 11.14 (4.38) a** | 6.98 (4.77) a**, b** | 14.02 (3.82) | 9.02 (5.01) c** |
Categorical fluency | 20.43 (5.63) | 21.86 (5.27) | 21.19 (5.57) | 18.98 (4.93) a** | 16.43 (5.26) a** | 21.62 (5.38) | 17.69 (5.23) c** |
TMT B-A time | 86.69 (51.35) | 68.66 (25.09) | 82.06 (39.72) a* | 105.58 (64.47) a** | 128.12 (76.56) a** | 73.51 (31.77) | 116.96 (71.38) c** |
SUVr tau (flortaucipir, AV1451)—entorhinal cortex | 2.08 (0.65) | 1.85 (0.37) | 2.06 (0.5) a** | 2.02 (0.64) | 2.84 (0.93) a**, b** | 1.93 (0.43) | 2.44 (0.89) c** |
SUVr tau (flortaucipir, AV1451)—inferior temporal cortex | 2.06 (0.52) | 1.9 (0.19) | 2.05 (0.33) a** | 2.01 (0.22) a* | 2.63 (1.03) a**, b** | 1.95 (0.26) | 2.32 (0.81) c** |
Amyloid (florbetapir-AV45) | 1.15 (0.22) | 1.01 (0.05) | 1.31 (0.17) a** | 0.99 (0.07) a* | 1.43 (0.21) a**, b** | 1.12 (0.18) | 1.21 (0.27) c** |
Informant complain (ECog memory) | 1.61 (0.67) | 1.34 (0.42) | 1.39 (0.46) | 2.07 (0.65) a** | 2.34 (0.81) a** | 1.36 (0.43) | 2.21 (0.75) c** |
Participant complain (ECog memory) | 1.87 (0.67) | 1.6 (0.49) | 1.82 (0.61) a* | 2.25 (0.74) a** | 2.38 (0.71) a** | 1.68 (0.54) | 2.32 (0.72) c** |
Awareness (participant-informant) | 0.26 (0.69) | 0.26 (0.51) | 0.43 (0.62) | 0.19 (0.77) | 0.04 (1.05) | 0.32 (0.56) | 0.11 (0.92) |
Awareness (objective-subjective) | −0.04 (1.44) | −0.19 (1.27) | 0.34 (1.39) a* | 0.3 (1.47) | −0.56 (1.74) b* | 0 (1.34) | −0.14 (1.66) |