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Table 3 Risk of having a minor allele in rs73375428 (G) or APOE ɛ4 on Aβ positivity

From: Identifying novel genetic variants for brain amyloid deposition: a genome-wide association study in the Korean population

 

rs73375428

APOE ɛ4

OR (95% CI)

p

OR (95% CI)

p

Total (n = 1190)

0.519 (0.404–0.666)

< 0.001

5.330 (4.188–6.788)

< 0.001

CU (n = 383)

0.486 (0.244–0.964)

0.030

3.885 (2.307–6.54)

< 0.001

aMCI (n = 330)

0.463 (0.286–0.749)

0.001

6.655 (4.101–10.8)

< 0.001

ADD (n = 477)

0.685 (0.370–1.270)

0.230

4.272 (2.428–7.516)

< 0.001

  1. Logistic regression analysis was adjusted for age and sex
  2. Abbreviations: ADD Alzheimer’s disease dementia, aMCI amnestic mild cognitive impairment, CU cognitive unimpaired, OR odds ratio