Fig. 2

Results of voxel-wise PET image analysis. T static maps showing a decreased Aβ deposition in participants with the minor allele of the rs73375428 variant (first row: thresholded by uncorrected p < 0.001 with cluster size > 20; second row: thresholded by family-wise rate-corrected p < 0.05) and b increased Aβ deposition in participants with APOE ɛ4 allele (thresholded by family-wise rate corrected p < 0.05). X and Z are based on MNI coordinates. Aβ, amyloid β; MNI, Montreal Neurological Institute