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Table 1 Participant demographics and clinical characteristics

From: Arterial stiffening acts synergistically with APOE genotype and AD biomarker status to influence memory in older adults without dementia

Variable Total sample, N = 193, mean ± SD or number (%)
Age 74.9 ± 5.9
Female 102 (53%)
Education 16.7 ± 2.4
APOE ε4+ 78 (40%)
Hispanic 18 (10%)
DRS 138.9 ± 4.3
MMSE 29.1 ± 1.3
CDR sum of boxes 0.3 ± 0.7
GDS 1.2 ± 1.7
Clinical Dx: normal 167 (87%)
Clinical Dx: MCI 26 (13%)
FSRP (%) 10.3 ± 7.9
Systolic BP 131.7 ± 18.6
Diastolic BP 80.4 ± 11.2
Pulse pressure 51.2 ± 13.9
PWV 8.9 ± 2.1
TIA 3 (2%)
Atrial fibrillation 20 (10%)
Diabetes 12 (6%)
CVD 27 (14%)
Smoking 4 (2%)
Antihypertensive medication use 94 (49%)
BMI 26.0 ± 5.6
N with CSF measures 123 (64%)
Interval from LP to PWV collection (years) 1.2 ± 0.9
42 812.2 ± 378.6
Tau 358.8 ± 190.1
AD-like tau/Aβ42 ratio 42 (34%)
  1. Abbreviations: CN cognitively normal, MCI mild cognitive impairment, SD standard deviation, APOE apolipoprotein E, DRS Dementia Rating Scale, MMSE Mini-Mental State Examination, CDR Clinical Dementia Rating Scale, GDS Geriatric Depression Scale, FSRP Framingham Stroke Risk Profile, bp blood pressure. Pulse pressure was calculated as systolic blood pressure minus diastolic blood pressure. PWV pulse wave velocity, CVD cardiovascular disease, BMI body mass index, CSF cerebrospinal fluid, Tau total tau; AD Alzheimer’s disease, amyloid beta