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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment

Fig. 2

A network landscape of COVID-19 and neurological diseases. a Network proximity analysis shows strong network associations between COVID-19 and neurological diseases. Heatmap shows the “shortest” network proximities in Z score (see the “Materials and methods” section). Smaller Z scores indicate smaller network proximities between the two gene sets. b Protein-protein interaction network of the SARS-CoV-2 and other human coronaviruses host factors and the Alzheimer’s disease-associated genes/proteins. SARS-CoV-2 entry factors, antiviral defense genes, and AD biomarkers are highlighted by their gene symbols

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