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Table 2 Group differences in long-term memory performance

From: Association of accelerated long-term forgetting and senescence-related blood-borne factors in asymptomatic individuals from families with autosomal dominant Alzheimer’s disease

  Mutation carriers Non-carriers p value Difference in mean 95% CI
Learning
 List learning trials 4.0 (4.0–5.0) 4.0 (4.0–5.0) 0.981 −0.01 −0.71 to 0.69
 List learning score 80.0 (80.0–86.7) 86.7 (80.0–86.7) 0.570 −1.38 −4.55 to 1.78
 Figure learning score 72.9 (63.2–80.6) 69.4 (60.4–76.4) 0.579 4.95 −2.61 to 12.51
30-min retention
 List 30-min recall 73.3 (66.7–80.0) 73.3 (70.0–80.0) 0.681 −3.46 −9.15 to 2.25
 Figure 30-min recall 69.4 (56.9–79.5) 66.7 (56.9–72.2) 0.418 3.36 −4.96 to 11.67
 List 30-min recognition 90.0 (73.3–93.3) 93.3 (83.3–93.3) 0.441 −3.64 −10.57 to 3.29
7-day retention
 List 7-day recall 53.3 (40.0–60.0) 66.7 (60.0–80.0) <0.001 −15.34 −22.23 to −8.46
 Figure 7-day recall 38.9 (33.3–52.8) 58.3 (47.9–60.4) 0.002 −12.31 −19.20 to −5.42
 List 7-day recognition 70.0 (53.3–80.0) 80.0 (73.3–90.0) 0.006 −11.52 −19.50 to −3.53
Long-term forgetting rate
 Forgetting rate in list recall 26.1 (18.2–34.1) 9.1 (0.0–14.1) <0.001 17.26 11.21 to 23.32
 Forgetting rate in figure recall 36.3 (28.4–48.1) 10.5 (7.1–20.4) <0.001 22.30 14.57 to 30.03
 Forgetting rate in list recognition 20.7 (14.3–28.9) 7.7 (0.0–18.3) 0.003 10.07 3.66 to 16.48
  1. Data are shown as medians (IQR). Multivariate linear regression adjusted for age, sex, and education was used to compare the between-group scores