| |
Mutation carriers
|
Non-carriers
|
p value
|
Difference in mean
|
95% CI
|
|---|
|
Learning
|
|
List learning trials
|
4.0 (4.0–5.0)
|
4.0 (4.0–5.0)
|
0.981
|
−0.01
|
−0.71 to 0.69
|
|
List learning score
|
80.0 (80.0–86.7)
|
86.7 (80.0–86.7)
|
0.570
|
−1.38
|
−4.55 to 1.78
|
|
Figure learning score
|
72.9 (63.2–80.6)
|
69.4 (60.4–76.4)
|
0.579
|
4.95
|
−2.61 to 12.51
|
|
30-min retention
|
|
List 30-min recall
|
73.3 (66.7–80.0)
|
73.3 (70.0–80.0)
|
0.681
|
−3.46
|
−9.15 to 2.25
|
|
Figure 30-min recall
|
69.4 (56.9–79.5)
|
66.7 (56.9–72.2)
|
0.418
|
3.36
|
−4.96 to 11.67
|
|
List 30-min recognition
|
90.0 (73.3–93.3)
|
93.3 (83.3–93.3)
|
0.441
|
−3.64
|
−10.57 to 3.29
|
|
7-day retention
|
|
List 7-day recall
|
53.3 (40.0–60.0)
|
66.7 (60.0–80.0)
|
<0.001
|
−15.34
|
−22.23 to −8.46
|
|
Figure 7-day recall
|
38.9 (33.3–52.8)
|
58.3 (47.9–60.4)
|
0.002
|
−12.31
|
−19.20 to −5.42
|
|
List 7-day recognition
|
70.0 (53.3–80.0)
|
80.0 (73.3–90.0)
|
0.006
|
−11.52
|
−19.50 to −3.53
|
|
Long-term forgetting rate
|
|
Forgetting rate in list recall
|
26.1 (18.2–34.1)
|
9.1 (0.0–14.1)
|
<0.001
|
17.26
|
11.21 to 23.32
|
|
Forgetting rate in figure recall
|
36.3 (28.4–48.1)
|
10.5 (7.1–20.4)
|
<0.001
|
22.30
|
14.57 to 30.03
|
|
Forgetting rate in list recognition
|
20.7 (14.3–28.9)
|
7.7 (0.0–18.3)
|
0.003
|
10.07
|
3.66 to 16.48
|
- Data are shown as medians (IQR). Multivariate linear regression adjusted for age, sex, and education was used to compare the between-group scores
