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Table 2 Group differences in long-term memory performance

From: Association of accelerated long-term forgetting and senescence-related blood-borne factors in asymptomatic individuals from families with autosomal dominant Alzheimer’s disease

 

Mutation carriers

Non-carriers

p value

Difference in mean

95% CI

Learning

 List learning trials

4.0 (4.0–5.0)

4.0 (4.0–5.0)

0.981

−0.01

−0.71 to 0.69

 List learning score

80.0 (80.0–86.7)

86.7 (80.0–86.7)

0.570

−1.38

−4.55 to 1.78

 Figure learning score

72.9 (63.2–80.6)

69.4 (60.4–76.4)

0.579

4.95

−2.61 to 12.51

30-min retention

 List 30-min recall

73.3 (66.7–80.0)

73.3 (70.0–80.0)

0.681

−3.46

−9.15 to 2.25

 Figure 30-min recall

69.4 (56.9–79.5)

66.7 (56.9–72.2)

0.418

3.36

−4.96 to 11.67

 List 30-min recognition

90.0 (73.3–93.3)

93.3 (83.3–93.3)

0.441

−3.64

−10.57 to 3.29

7-day retention

 List 7-day recall

53.3 (40.0–60.0)

66.7 (60.0–80.0)

<0.001

−15.34

−22.23 to −8.46

 Figure 7-day recall

38.9 (33.3–52.8)

58.3 (47.9–60.4)

0.002

−12.31

−19.20 to −5.42

 List 7-day recognition

70.0 (53.3–80.0)

80.0 (73.3–90.0)

0.006

−11.52

−19.50 to −3.53

Long-term forgetting rate

 Forgetting rate in list recall

26.1 (18.2–34.1)

9.1 (0.0–14.1)

<0.001

17.26

11.21 to 23.32

 Forgetting rate in figure recall

36.3 (28.4–48.1)

10.5 (7.1–20.4)

<0.001

22.30

14.57 to 30.03

 Forgetting rate in list recognition

20.7 (14.3–28.9)

7.7 (0.0–18.3)

0.003

10.07

3.66 to 16.48

  1. Data are shown as medians (IQR). Multivariate linear regression adjusted for age, sex, and education was used to compare the between-group scores