Table 3 Reasons for neurologists on how they used the sNfL result in case they perceived it as useful

Confirm AD

N = 10

Exclude neurodegeneration

N = 8

Confirm neurological disorder

N = 3

Confirm neurodegeneration, e.g., MCI, FTD, other

N = 5

Confirm SCD

N = 6

Exclude AD

N = 1

Support AD

N = 2

Confirm no neurodegeneration

N = 4

Exclude neurodegeneration

N = 1

Support neurodegeneration

N = 1

To reassure patient

N = 4

For follow-up

N = 1

Exclude FTD, confirm AD

N = 1

Exclude FTD

N = 2

Due to recent heart attack

N = 1

For follow-up

N = 1

Less support for FTD

N = 1

Other

N = 1

Exclude AD

N = 1

Exclude CTE

N = 1

Support SCD

N = 1

For patient management

N = 1

Indication for vessel damage

N = 1