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Table 2 The association of neurodegenerative pathologies in the MTL with MTL volume/thickness measures in β-amyloid negative individuals. All pathologies are entered in one model, with time between scan and death and gender as covariates. Spearman rank values are reported in the table

From: Pathological drivers of neurodegeneration in suspected non-Alzheimer’s disease pathophysiology

 

Whole Hippo

Ant Hippo

Post Hippo

ERC

BA35

BA36

PHC

ADNI

 NP

−0.11

−0.12

0.08

0.14

−0.13

−0.14

−0.31

 Tau

0.02

0.09

−0.17

−0.31

−0.11

0.08

0.05

 α-synuclein

0.00

−0.08

0.35

0.23

0.22

−0.08

0.26

 TDP-43

−0.48

−0.40

−0.41

0.00

0.14

0.57

0.49

UPenn

 NP

0.16

0.14

0.13

0.20

0.17

0.09

0.32*

 Tau

0.40**

0.34*

0.46***

0.34*

0.31*

−0.29

−0.08

 α-synuclein

−0.10

−0.03

−0.13

−0.11

−0.14

−0.16

−0.15

 TDP-43

0.30*

0.33*

−0.26

−0.13

−0.25

−0.22

−0.11

  1. p<0.10, *p<0.05, **p<0.01, ***p<0.001. NP neuritic plaques, TDP TAR DNA-binding protein, Ant anterior, Post posterior, ERC entorhinal cortex, BA Brodmann area, PHC parahippocampal cortex