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Table 1 Inaugural complaint and cognitive phenotype at diagnosis in young and old-AD patients

From: Characterization of the initial complaint and care pathways prior to diagnosis in very young sporadic Alzheimer’s disease

  1. *Data available for 61 patients with young-AD
  2. Four cognitive presentations have been identified from the results of the neuropsychological assessments:
  3. -Limbic characterized by hippocampal amnestic syndrome, [8]
  4. -Biparietal dysfunction characterized by a visuospatial deficit, dyspraxia, dysgraphia, logopenic aphasia, and deficit of auditory-verbal short-term memory [2, 9]
  5. -Logopenic variant primary progressive aphasia according to the clinical criteria of Gorno-Tempini et al. 2011 [10].
  6. -Visual spatial dysfunction, known as posterior cortical atrophy (PCA) or “Benson’s disease” characterized by oculomotor apraxia, optic ataxia, dressing apraxia, environmental disorientation, abnormal anti-saccades, neglect, constructional difficulty, simultanagnosia, visual agnosia, and prosopagnosia [11, 12].
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Alzheimer's Research & Therapy

ISSN: 1758-9193