Table 3 Characteristics of study cohort 2 and baseline statistics of CSF measurements

Age

66.86 ± 10.95

68.29 ± 11.20

0.6928*

0.7442^$

 Women

9 (42.9%)

6 (35.3%)

 Men

12 (57.1%)

11 (64.7%)

 CSF GPNMB [pg/ml]

8074 ± 3358

8620 ± 3577

0.6845^#

 ε2/ε2

–

–

 ε2/ε3

2

–

 ε2/ε4

1

1

 ε3/ε3

13

7

 ε3/ε4

4

8

 ε4/ε4

1

1

 ≥ 1 APOE ε4 allele, n (%)

6 (28.6%)

10 (58.8%)

0.0990^$

 CSF p-Tau [pg/ml]

52.52 ± 26.59

69.76 ± 27.39

0.0367^#

 CSF t-Tau [pg/ml]

362.3 ± 258.4

578.0 ± 339.1

0.0225^#

 CSF Aβ38 [pg/ml]

2848 ± 946.1

2509 ± 734.8

0.2810^#

 CSF Aβ40 [pg/ml]

9294 ± 2851

8343 ± 2575

0.2929*

 vCSF Aβ42 [pg/ml]

796.5 ± 336.9

441.2 ± 157.3

0.0002^#

 CSF Aβ ratio 42/40

0.08529 ± 0.01939

0.05433 ± 0.01949

<  0.0001^#