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Table 2 Association between lifestyle factors and AD biomarkers

From: Associations of healthy lifestyles with cerebrospinal fluid biomarkers of Alzheimer’s disease pathology in cognitively intact older adults: the CABLE study

  Current smoking P* P#
Yes (n = 220) No (n = 888)
CSF Aβ42 162.25 ± 71.75 169.01 ± 81.40 0.47 0.17
CSF tau 170.81 ± 70.35 171.43 ± 77.54 0.78 0.29
CSF p-tau 36.57 ± 8.57 36.89 ± 9.23 0.83 0.47
  Alcohol consumption   
Harmful drinking (n = 157) No or moderate drinking (n = 951)   
CSF Aβ42 178.53 ± 94.72 165.82 ± 76.65 0.35 0.44
CSF tau 175.84 ± 80.03 170.55 ± 75.48 0.63 0.12
CSF p-tau 37.11 ± 10.00 36.79 ± 8.95 0.97 0.35
  Absence of social isolation   
No (n = 240) Yes (n = 868)   
CSF Aβ42 175.89 ± 89.94 165.33 ± 76.30 0.27 0.19
CSF tau 188.17 ± 76.40 166.67 ± 75.44 < 0.01 < 0.01
CSF p-tau 39.11 ± 9.09 36.21 ± 9.01 < 0.01 < 0.01
  Regular physical activity   
  No (n = 833) Yes (n = 275)   
CSF Aβ42 163.96 ± 76.65 178.96 ± 87.03 0.03 0.01
CSF tau 173.73 ± 78.20 164.03 ± 69.15 0.10 0.04
CSF p-tau 37.25 ± 9.32 35.57 ± 8.28 0.01 < 0.01
  1. *Unadjusted
  2. #Adjusted for age, sex, educational level, and APOE ε4 status