| |
Current smoking
|
P*
|
P#
|
|
Yes (n = 220)
|
No (n = 888)
|
|
CSF Aβ42
|
162.25 ± 71.75
|
169.01 ± 81.40
|
0.47
|
0.17
|
|
CSF tau
|
170.81 ± 70.35
|
171.43 ± 77.54
|
0.78
|
0.29
|
|
CSF p-tau
|
36.57 ± 8.57
|
36.89 ± 9.23
|
0.83
|
0.47
|
| |
Alcohol consumption
| | |
|
Harmful drinking (n = 157)
|
No or moderate drinking (n = 951)
| | |
|
CSF Aβ42
|
178.53 ± 94.72
|
165.82 ± 76.65
|
0.35
|
0.44
|
|
CSF tau
|
175.84 ± 80.03
|
170.55 ± 75.48
|
0.63
|
0.12
|
|
CSF p-tau
|
37.11 ± 10.00
|
36.79 ± 8.95
|
0.97
|
0.35
|
| |
Absence of social isolation
| | |
|
No (n = 240)
|
Yes (n = 868)
| | |
|
CSF Aβ42
|
175.89 ± 89.94
|
165.33 ± 76.30
|
0.27
|
0.19
|
|
CSF tau
|
188.17 ± 76.40
|
166.67 ± 75.44
|
< 0.01
|
< 0.01
|
|
CSF p-tau
|
39.11 ± 9.09
|
36.21 ± 9.01
|
< 0.01
|
< 0.01
|
| |
Regular physical activity
| | |
| |
No (n = 833)
|
Yes (n = 275)
| | |
|
CSF Aβ42
|
163.96 ± 76.65
|
178.96 ± 87.03
|
0.03
|
0.01
|
|
CSF tau
|
173.73 ± 78.20
|
164.03 ± 69.15
|
0.10
|
0.04
|
|
CSF p-tau
|
37.25 ± 9.32
|
35.57 ± 8.28
|
0.01
|
< 0.01
|
- *Unadjusted
- #Adjusted for age, sex, educational level, and APOE ε4 status
