Associations of healthy lifestyles with cerebrospinal fluid biomarkers of Alzheimer’s disease pathology in cognitively intact older adults: the CABLE study

Table 1 Characteristics of study subjects

Characteristic	No. (n = 1108)
Age (years)	61.1 ± 11.0 (41 to 89)
Sex (F/M)	461/647
Education (years)	9.8 ± 4.4
CM-MMSE	28.2 ± 1.9
MoCA	23.8 ± 4.0
^*APOE ε4 (carriers/non-carriers)	161/800
^*CSF Aβ42 (pg/ml)	167.6 ± 79.5
^*CSF Aβ40 (pg/ml)	5981.8 ± 2728.5
^*CSF tau (pg/ml)	171.3 ± 76.1
^*CSF p-tau (pg/ml)	36.8 ± 9.1
Healthy lifestyle factors (n, %)
No current smoking	888 (80.1%)
No or moderate drinking	951 (85.8%)
Regular physical activity	275 (24.8%)
Absence of social isolation	868 (78.3%)
No. of healthy lifestyle factors (n, %)
0	9 (0.8%)
1	84 (7.6%)
2	302 (27.3%)
3	558 (50.4%)
4	155 (14.0%)

Summarized as mean ± standard deviation (SD) for continuous data and count for categorical data. Abbreviations: CSF, cerebrospinal fluid; MMSE, Mini-Mental State Examination; p-tau, phosphorylated tau
* Data were missing for CSF Aβ42 (n = 162, 14.6%), CSF Aβ40 (n = 198, 17.9%), CSF tau (n = 92, 8.3%), CSF p-tau (n = 90, 8.1%), and APOE ε4 statues (n = 147, 13.3%)

ISSN: 1758-9193