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Table 3 Treatment, complications and outcome

From: COVID-19 in adults with dementia: clinical features and risk factors of mortality—a clinical cohort study on 125 patients

 

Total (n = 125)

Survivors (n = 97)

Non-survivors (n = 28)

P

Covid severity*

   

0.001

 Mild

37.6% (47)

48.5% (47)

0.0% (0)

 

 Moderate

27.2% (34)

35.0% (34)

0.0% (0)

 

 Severe

35.2% (44)

16.5% (16)

100% (28)

 

 Treatment

Oxygen therapy

60.0% (75)

50.5% (49)

92.9% (26)

< 0.0001

Maximal flow (L/min)

3.0 (2.0–6.0)

3.0 (2.0–6.0)

5.0 (2.5–15.0)

0.018

Antibiotics use

61.6% (77)

57.7% (56)

75.0% (21)

0.074

Combination of antibiotics

33.6% (42)

29.9% (29)

46.4% (13)

0.082

Beta-lactamine

54.4% (68)

50.5% (49)

67.9% (19)

0.079

 Macrolides

37.6% (47)

35.1% (34)

46.4% (13)

0.279

2nd line antibiotics

17.6% (22)

14.4% (14)

28.6% (8)

0.096

 Steroids

8.0% (10)

8.2% (8)

7.1% (2)

1.000

Hydroxychloroquine

16.8% (21)

16.5% (16)

17.9% (5)

1.000

 Neuroleptics

4.8% (6)

5.2% (5)

3.6% (1)

0.678

Complications

 ARDS

25.6% (32)

6.2% (6)

92.9% (26)

< 0.0001

Cardiac injury

13.6% (17)

9.3% (9)

28.6% (8)

0.024

 ACKI

16.8% (21)

12.4% (12)

32.1% (9)

0.021

Bacterial superinfection

14.4% (18)

11.3% (11)

25.0% (7)

0.122

Behavioural disorder

19.2% (24)

21.6% (21)

10.7% (3)

0.278

Diabetic ketoacidosis

2.4% (3)

3.1% (3)

0.0% (0)

1.000

 Seizure

2.4% (3)

2.1% (2)

3.6% (1)

0.536

 Stroke

2.4% (3)

2.1% (2)

3.6% (1)

1.000

 Outcome

Total (n=125)

Survivors (n=97)

Non-survivors (n=28)

 

Total mortality

22.4% (28)

   

Delay admission-death

  

8.5 (3.7–16)

Length of stay

 

16 (11–19.7)

  

Discharge home before end of follow-up

40.2% (39)

  
  1. Data are median (IQI), % (n). P values > 0.05 (bold) indicates significant differences between survivors and non-survivors
  2. *COVID severity defined according to WHO guidelines
  3. ACKI acute kidney injury, ARDS acute respiratory distress syndrome