Fig. 3From: Strategies to reduce sample sizes in Alzheimer’s disease primary and secondary prevention trials using longitudinal amyloid PET imagingSample size requirements (per arm). Relationship between achieved statistical power and number of participants required in three anti-amyloid hypothetical trial scenarios for the general population (top row) or focusing on APOE-ε4 carriers only (bottom row). The dotted line represents the desired power of 1-β = 80%Back to article page