Fig. 1

The pie chart illustrates the distribution of each ATN class in a memory-clinic derived sample of patients. a The cut-off values used to define the ATN classes were 798 pg/mL for Aβ42, 87 pg/mL for p181-tau, and 465 pg/mL for t-tau. b The cut-off value is the same for Aβ42, but lowered for tau: 58.9 pg/mL for p181-tau, 354 pg/mL for t-tau