Fig. 1

Plasma Nfl and t-tau in the differential diagnosis of neurodegenerative dementia. Dot plot displaying a Nfl and b t-tau concentrations in the differential diagnosis of neurodegenerative dementia. c Statistical significance derived from a multi-comparative analysis corrected for covariates for Nfl and t-tau among the diagnostic groups (linear regression models were used, as explained in the “Statistical analysis” section). The Tukey-corrected p values for each pair of diagnostic group comparison are indicated. HC, healthy controls; NND, neurological diseases without dementia; NND-Dem, neurological diseases with dementia; AD, Alzheimer’s disease; CJD, Creutzfeldt-Jakob disease; DLB/PDD, dementia with Lewy bodies/Parkinson’s disease dementia; FTD, fronto-temporal dementia; VaD, vascular dementia; Nfl, neurofilament light; t-tau, total-tau; f, female; m, male; SD, standard deviation