LF | Analyte | Full name | Entry# | Previously reported AD association |
---|---|---|---|---|
Proteomics | ||||
1 | NRN1 | Neuritin isoform 1 precursor | Q9NPD7 | |
1 | SMS | Spermine synthase | P52788 | Yes [37] |
1 | NXPH4 | Neurexophilin-4 | O95158 | |
1 | LTBP1 | Latent-transforming growth factor beta-binding protein 1 | Q14766 | |
1 | CLUS | Clusterin | P10909 | Yes [38] |
1 | NPDC1 | Neural proliferation differentiation and control protein 1 | Q9NQX5 | |
1 | PNOC | Prepronociceptin | Q13519 | |
1 | DYL2 | Dynein light chain 2, cytoplasmic | Q96FJ2 | |
1 | PDGFB | Platelet-derived growth factor subunit B | P01127 | Yes [39] |
1 | SAP3 | Sphingolipid activator protein 3 | P17900 | |
1 | MT1E | Metallothionein-1E | P04732 | Yes [40] |
1 | PCSK1 | Neuroendocrine convertase 1 | P29120 | Yes [41] |
1 | TAGL | Transgelin-2 | P37802 | Yes [42] |
1 | MT3 | Metallothionein-3 | P25713 | Yes [40] |
1 | LY6H | Lymphocyte antigen 6H | O94772 | |
2 | SAMP | Spindle-associated membrane protein 1 | Q5SNT2 | |
2 | VTNC | Vitronectin | P04004 | Yes [43] |
2 | KNG1 | Kininogen-1 | P01042 | |
2 | FETUA | Alpha-2-HS-glycoprotein | P02765 | Yes [44] |
2 | HELZ | Probable helicase with zinc finger domain | P42694 | |
2 | PLMN | Plasminogen | P00747 | Yes [45] |
2 | PGRP2 | N-acetylmuramoyl-L-alanine amidase | Q96PD5 | |
2 | AFAM | Afamin | P43652 | Yes [44] |
2 | ITIH1 | Inter-alpha-trypsin inhibitor heavy chain H1 | P19827 | Yes [46] |
2 | CO8B | Complement component C8 beta chain | P07358 | Yes [47] |
2 | FIBA | Fibrinogen alpha chain | P02671 | Yes [48] |
2 | CO6 | Complement component C6 | P13671 | Yes [47] |
2 | ITIH4 | Inter-alpha-trypsin inhibitor heavy chain H4 | Q14624 | Yes [46] |
3 | EPDR1 | Mammalian ependymin-related protein 1 | Q9UM22 | |
3 | SIAE | Sialate O-acetylesterase | Q9HAT2 | |
4 | X1433Z | 14-3-3 protein zeta/delta | P63104 | Yes [49] |
4 | S10A6 | Protein S100-A6 | P06703 | Yes [50] |
4 | PRDX6 | Peroxiredoxin-6 | P30041 | Yes [51] |
5 | VTM2A | V-set and transmembrane domain-containing protein 2A | Q8TAG5 | |
5 | S10A6 | Protein S100-A6 | P06703 | Yes [50] |
5 | CMGA | Chromogranin-A | P10645 | Yes [52] |
5 | ZP2 | Zona pellucida sperm-binding protein 2 | Q05996 | |
5 | SLIK1 | SLIT and NTRK-like protein 1 | Q96PX8 | Yes [53] |
Neuroinflammation | ||||
1 | sVCAM-1 | Circulating vascular cell adhesion molecule-1 | P19320 | Yes [54] |
1 | IL-15 | Interleukin-15 | P40933 | Yes [54] |
1 | sICAM-1 | Soluble intracellular adhesion molecule-1 | P05362 | Yes [54] |
2 | SAA | Serum amyloid A | P0DJI8 | Yes [55] |
2 | PIGF_1R | Insulin-like growth factor 1 receptor | P08069 | Yes [56] |
3 | PIGF_1R | Insulin-like growth factor 1 receptor | P08069 | Yes [56] |
4 | IL-16 | Interleukin-16 | Q14005 | Yes [57] |
5 | MCP-1 | Monocyte chemoattractant protein-1 | P13500 | Yes [54] |
5 | PIGF_1R | Insulin-like growth factor 1 receptor | P08069 | Yes [56] |
One-carbon metabolism | ||||
1 | MTHF | 5-methyltetrahydrofolate | 20,612 | Yes [58] |
1 | SAH | S-adenosyl-L-homocysteine | 16,680 | Yes [59] |
2 | CYST | Total cysteine | 15,356 | Yes [60] |
3 | SAH | S-adenosyl-L-homocysteine | 16,680 | Yes [59] |
4 | CYST | Total cysteine | 15,356 | Yes [60] |
5 | CYST | Total cysteine | 15,356 | Yes [60] |
Metabolomics | ||||
1 | N/A | Glycoproteins | 17,089 | Yes [61] |
2 | N/A | Alanine | 16,449 | Yes [62] |
2 | N/A | Valine | 27,266 | |
2 | N/A | Glycoproteins | 17,089 | Yes [61] |
3 | N/A | Inositol | 24,848 | |
4 | N/A | Glycoproteins | 17,089 | Yes [61] |
5 | N/A | Formic acid | 30,751 | |
5 | S69 | Unidentified metabolite | N/A | N/A |
5 | N/A | Acetoacetic acid | 15,344 | Yes [63] |
Lipidomics | ||||
1 | PC 32:0 | 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine | N/A | Yes [64] |
2 | SE 27:1 18:2 | Cholesteryl ester | N/A | |
3 | PC 32:0 | 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine | N/A | Yes [64] |
4 | SE 27:1 18:2 | Cholesteryl ester | N/A | |
4 | SE 27:1 20:4 | Cholesteryl ester | N/A | |
4 | SE 27:1 16:0 | Cholesteryl ester | N/A | |
5 | LPG 20:1 | 1-(11Z-eicosenoyl)-glycero-3-phospho-(1′-sn-glycerol) | N/A |