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Table 2 Study cohort

From: An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer’s disease

 

Whole cohort (n = 120)

Control (n = 79)

AD (n = 41)

P value

Age (years)

70.37 ± 7.92

68.42 ± 8.23

74.15 ± 5.7

< 0.001

Sex (%, female)

64.2

67.1

58.5

0.354

Education (years)

12.37 ± 2.7

12.51 ± 2.7

12.10 ± 12.1

0.404

CDR-SoB

1.054 ± 1.6

0.456 ± 0.9

2.20 ± 2.0

< 0.001

MMSE

26.94 ± 3.08

27.85 ± 2.28

25.15 ± 3.71

< 0.001

P-Tau/Aβ1-42 ratio

0.088 ± 0.082

0.048 ± 0.127

0.165 ± 0.104

< 0.001

APOEε4 carrier (%)

29.6

17.7

56.1

< 0.001

  1. Characteristics of the study cohort. Mean values ± standard deviation are presented. Per definition, participants within the AD group all presented a positive AD CSF biomarker profile, defined by a P-tau/Aβ1-42 ratio > 0.0779. P value was obtained from t test for continuous variables or chi-square statistics for sex