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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer’s disease

Fig. 5

Clinical predictions. Binary logistic regression models to improve clinical predictions. a ROC curves and AUCs for the reference model including APOE status (green) and the final prediction model of AD pathology (red) obtained after addition of four analytes (14-3-3 zeta/delta, clusterin, interleukin-15, and transgelin-2) selected by the MOFA model. b Confusion matrix of the final prediction model of AD. c ROC curves and AUCs for the reference model including APOE status (green) and the final prediction model of cognitive decline (red) obtained after addition of four analytes (14-3-3 zeta/delta, clusterin, cholesteryl ester 27:1 16:0 and monocyte chemoattractant protein-1) selected by the MOFA model. d Confusion matrix of the final prediction model of cognitive decline

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Alzheimer's Research & Therapy

ISSN: 1758-9193