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Table 2 Sub-cohort demographics

From: Core Alzheimer’s disease cerebrospinal fluid biomarker assays are not affected by aspiration or gravity drip extraction methods

 

Total sample

CN

MCI

AD

p value

N (%)

50

36 (72)

8 (16)

6 (12)

 

PET-Aβ+ (%)

23 (46)

12 (35)

5 (71)

6 (100)

0.0029

Gender male, N (%)

21 (42)

14 (39)

3 (38)

4 (67)

0.54

Mean age, years (SD)

72.8 (5.8)

73.1 (5.6)

73.5 (7.3)

70.5 (5.3)

0.42

APOE ε4 carriage, N (%)

16 (32)

9 (25)

4 (50)

4 (50)

0.26

Median MMSE, (MAD)

28 (3)

29 (1.5)

27 (2.2)

23.5 (4.4)

0.0019

Median CDR score, (MAD)

0 (0)

0 (0)

0.5 (0)

1 (0.4)

< 0.0001

  1. Abbreviations: N number, CN cognitively normal, MCI mild cognitive impairment, AD Alzheimer’s disease, APOE ε4 Apolipoprotein E epsilon 4 allele, APOE ε4 Carriage, N (%) number of participants with at least one APOE ε4 allele, MMSE Mini-Mental State Examination, CDR Clinical Dementia Rating, IQR inter-quartile range, MAD maximum absolute deviation, PET-Aβ Positron Emission Tomography Amyloid Beta. p value determined by t-test (age), chi-square analyses (PET-Aβ status, APOE ε4, and gender) and Kruskal-Wallis tests (CDR score and MMSE)