| Total sample | CN | MCI | AD | p value |
---|
N (%) | 50 | 36 (72) | 8 (16) | 6 (12) | |
PET-Aβ+ (%) | 23 (46) | 12 (35) | 5 (71) | 6 (100) | 0.0029 |
Gender male, N (%) | 21 (42) | 14 (39) | 3 (38) | 4 (67) | 0.54 |
Mean age, years (SD) | 72.8 (5.8) | 73.1 (5.6) | 73.5 (7.3) | 70.5 (5.3) | 0.42 |
APOE ε4 carriage, N (%) | 16 (32) | 9 (25) | 4 (50) | 4 (50) | 0.26 |
Median MMSE, (MAD) | 28 (3) | 29 (1.5) | 27 (2.2) | 23.5 (4.4) | 0.0019 |
Median CDR score, (MAD) | 0 (0) | 0 (0) | 0.5 (0) | 1 (0.4) | < 0.0001 |
- Abbreviations: N number, CN cognitively normal, MCI mild cognitive impairment, AD Alzheimer’s disease, APOE ε4 Apolipoprotein E epsilon 4 allele, APOE ε4 Carriage, N (%) number of participants with at least one APOE ε4 allele, MMSE Mini-Mental State Examination, CDR Clinical Dementia Rating, IQR inter-quartile range, MAD maximum absolute deviation, PET-Aβ Positron Emission Tomography Amyloid Beta. p value determined by t-test (age), chi-square analyses (PET-Aβ status, APOE ε4, and gender) and Kruskal-Wallis tests (CDR score and MMSE)