Table 2 Correlations (rho) of plasma NfL and plasma p-tau181 levels with other biomarkers

From: Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer’s disease pathology and clinical disease progression

	Plasma NfL		Plasma p-tau181
	rho	p-value	rho	p-value
CN participants
CSF Aβ_1–42	0.130	0.235	− 0.021	0.849
CSF Aβ_1–42/Aβ_1–40	−0.074	0.510	− 0.0173	0.128
CSF p-tau181	0.242	0.026	0.326	0.003
CSF tau	0.26	0.016	0.213	0.055
Plasma NfL			0.317	< 0.001
Plasma p-tau181	0.317	< 0.001
Hippocampal volume	0.027	0.817	0.023	0.849
CI participants
CSF Aβ_1–42	−0.052	0.584	0.415	< 0.001
CSF Aβ_1–42/Aβ_1–40	−0.006	0.950	− 0.328	< 0.001
CSF p-tau181	0.148	0.116	0.417	< 0.001
CSF tau	0.233	0.013	0.496	< 0.001
Plasma NfL			0.336	< 0.001
Plasma p-tau181	0.336	< 0.001
Hippocampal volume	− 0.349	0.002	−0.135	0.235

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