Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport

Table 5 Spearman’s correlation analysis between KIF5 members when normalized to GAPDH in human AD frontal cortex samples

Sample type			Sample size (n)	Correlation coefficient (r)	Significance (P)
C/AD and AD	KIF5A	KIF5B	24	0.6113	0.0015**
C/AD and AD	KIF5A	KIF5C	24	0.8991	< 0.0001***
C/AD and AD	KIF5B	KIF5C	24	0.6252	0.0011**
AD	KIF5A	KIF5B	12	0.6084	0.0358*
AD	KIF5A	KIF5C	12	0.8462	0.0005***
AD	KIF5B	KIF5C	12	0.7413	0.0058**
C/AD	KIF5A	KIF5B	12	0.6713	0.0168*
C/AD	KIF5A	KIF5C	12	0.9301	< 0.0001***
C/AD	KIF5B	KIF5C	12	0.5455	0.0666

ISSN: 1758-9193