Table 2 Demographics, PMI, and clinical diagnosis for AD-DS and C/AD-DS frontal cortex samples

C/AD-DS 1*

Female

95

2.5

Cognitively normal

C/AD-DS 2*

Male

93

3

Cognitively normal

C/AD-DS 3*

Male

79

3

Cognitively normal

C/AD-DS 4

Male

74

3.3

Cognitively normal

C/AD-DS 5*

Female

58

3.1

Cognitively normal

C/AD-DS 6*

Female

49

7

Cognitively normal

C/AD-DS 7*

Female

54

6

Cognitively normal

C/AD-DS 8*

Female

59

5.9

Cognitively normal

C/AD-DS 9*

Male

48

6

Cognitively normal

C/AD-DS 10*

Male

57

16

Cognitively normal

C/AD-DS 11*

Male

58

9

Cognitively normal

C/AD-DS 12

Female

50

7

Cognitively normal

C/AD-DS 13

Female

46

18

Cognitively normal

C/AD-DS 14

Female

39

19

Cognitively normal

C/AD-DS 15

Male

59

5.9

Cognitively normal

C/AD-DS 16

Male

59

15.8

Cognitively normal

C/AD-DS 17

Female

48

8

Cognitively normal

C/AD-DS 18

Female

51

21

Cognitively normal

C/AD-DS 19

Female

57

7

Cognitively normal

Mean ± SEM

11F/8M

60 ± 3

8.8 ± 1.4

AD-DS 1

Female

45

2.7

Trisomy 21 with AD

AD-DS 2

Male

46

6.4

Trisomy 21 with AD

AD-DS 3

Male

49

2.2

Trisomy 21 with AD

AD-DS 4

Male

55

4.5

Trisomy 21 with AD

AD-DS 5

Female

57

6

Trisomy 21 with AD

AD-DS 6

Female

46

7

Trisomy 21 with AD

AD-DS 7

Male

65

10

Trisomy 21 with AD

AD-DS 8

Male

56

16

Trisomy 21 with AD

AD-DS 9

Male

55

12

Trisomy 21 with AD

AD-DS 10

Male

57

5

Trisomy 21 with AD

AD-DS 11

Female

51

4

Trisomy 21 with AD

AD-DS 12

Male

57

3

Trisomy 21 with AD

AD-DS 13

Male

41

15

Trisomy 21 with AD

AD-DS 14

Male

64

20

Trisomy 21 with AD

AD-DS 15

Male

51

15.7

Trisomy 21 with AD

AD-DS 16

Male

50

22.8

Trisomy 21 with AD

AD-DS 17

Female

45

2.75

Trisomy 21 with AD

AD-DS 18

Female

47

6.5

Trisomy 21 with AD

AD-DS 19

Female

50

5

Trisomy 21 with AD

AD-DS 20

Female

52

4.37

Trisomy 21 with AD

AD-DS 21

Female

62

2.42

Trisomy 21 with AD

Mean ± SEM

9F/12M

52 ± 1

8.3 ± 1.4