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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport

Fig. 5

The levels of KIF5 family members were not changed in the J20 mouse or the APP KO mouse brain. a As in Fig. 5, Western blotting was used to measure the levels of KIF5 family members in the brains of 6-month-old J20 mice and their age-matched controls. APP was also probed; β-actin was used as a loading control. b The levels of KIF5 members were examined in the brains of 12-month-old APP KO mice and their age-matched control wild-type mice. The left panels show representative immunoblots, while the right panels display the quantitation and statistical analysis. Mann-Whitney test. n = 4–5 for each; *P < 0.05. n.s., non-significant

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