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Table 1 Sample demographics

From: Association of CSF proteins with tau and amyloid β levels in asymptomatic 70-year-olds

   Aβ42/Aβ40 ratio CDR score
All A+
< 0.082
A−
> 0.082
≥ 0.5 0
n 307 56 251 57 250
Sex (F/M) 149/158 25/31 124/127 23/34 126/124
Aβ42 (pg/ml)a 753 [145–1200] 396 [145–628] 792 [304–1200] 735 [195–1180] 761 [145–1200]
Total tau (pg/ml)a 299 [115–963] 412 [225–963] 287 [115–800] 303 [144–634] 298 [115–963]
Phospho-tau (pg/ml)a 48 [18–128] 59 [35–128] 45 [18–113] 49 [23–84] 47 [18–128]
Aβ40 (pg/ml)a 6262 [2752–9968] 6618 [3661–9760] 6121 [2752–9968] 6042 [3175–8268] 6271 [2752–9968]
Aβ42/Aβ40 ratio 0.123 [0.022–0.210] 0.061 [0.022–0.081] 0.129 [0.083–0.210] 0.122 [0.034–0.199] 0.123 [0.022–0.210]
NfL (pg/ml)a 732 [255–12,312] 783 [302–3124] 711 [255–12,312] 720 [255–6233] 724 [276–12,312]
Neurogranin (pg/ml)a 197 [54–513] 224 [120–410] 188 [54–513] 199 [54–374] 196 [72–513]
APOE ε4 carrier (Y/N/NA) 108/196/3 38/17/1 70/179/2 27/30/0 81/166/3
APOE genotype (22/32/33/42/43/44/NA) 1/37/158/4/95/9/3 0/2/15/2/29/7/1 1/35/143/2/66/2/2 0/6/24/1/23/3/0 1/31/134/3/74/6/3
CDR score (0/0.5/1) 250/56/1 45/11/0 205/45/1 0/56/1 250/0/0
  1. aProtein and peptide concentrations are presented in the format, median [range]