Skip to main content

Table 1 Demographic characteristics of participants

From: Cognitive trajectories of patients with focal ß-amyloid deposition

Uptake grade No-FMM uptake (n = 122) Focal-FMM uptake (n = 45) Diffuse-FMM uptake (n = 73) p
No vs Focal uptake
p
No vs Diffuse uptake
p
Focal vs Diffuse uptake
Age (Mean ± SD) 69.2 ± 8.6 73.6 ± 8.0 71.1 ± 8.4 0.008 0.360 0.341
Men (%) 51 (41.8) 13 (28.9) 33 (45.2) 0.387 1.000 0.236
Education, years (Mean ± SD) 10.1 ± 5.0 10.3 ± 5.0 10.9 ± 4.5 1.000 0.822 1.000
APOE ε4 carrier (N = 236) 17/119 (14.3) 19/45 (42.2) 40/72 (55.6) < 0.001 <  0.001 0.487
Vascular risk factors
Hypertension (%) 59 (48.4) 19 (42.2) 26 (35.6) 1.000 0.250 1.000
Diabetes (%) 20 (16.4) 5 (11.1) 11 (15.1) 1.000 1.000 1.000
Hyperlipidemia (%) 45 (36.9) 14 (31.1) 10 (13.7) 1.000 0.002 0.069
Diagnosis     < 0.001 <  0.001 0.005
CU (%) 83 (68.0) 19 (42.2) 10 (13.7)    
aMCI (%) 34 (27.9) 11 (24.4) 33 (45.2)    
ADD (%) 5 (4.1) 15 (33.3) 30 (41.1)    
  1. P values were corrected for multiple comparisons using the Bonferroni method
  2. FMM 18F-flutemetamol, APOE ε4 apolipoprotein ε4, CU cognitively unimpaired, aMCI amnestic mild cognitive impairment, ADD Alzheimer’s disease dementia
\