Fig. 1

Multiple linear regression between HOMA2, hippocampal rCMRGlc and total grey matter volume. a The inverse association between log transformed HOMA2 hippocampal rCMRGlc, in a multiple regression model corrected by age and gender (R² = 0.19, p = 0.01). Log transformed HOMA2 was negatively associated with total grey matter volumes (R² = 0.37, p = 0.01), in a multiple regression model corrected by age and gender (b). rCMRGlc is expressed in μmol/g/min, total grey matter volumes are expressed in mm³