TY - JOUR AU - Femminella, Grazia Daniela AU - Livingston, Nicholas R. AU - Raza, Sanara AU - van der Doef, Thalia AU - Frangou, Eleni AU - Love, Sharon AU - Busza, Gail AU - Calsolaro, Valeria AU - Carver, Stefan AU - Holmes, Clive AU - Ritchie, Craig W. AU - Lawrence, Robert M. AU - McFarlane, Brady AU - Tadros, George AU - Ridha, Basil H. AU - Bannister, Carol AU - Walker, Zuzana AU - Archer, Hilary AU - Coulthard, Elizabeth AU - Underwood, Ben AU - Prasanna, Aparna AU - Koranteng, Paul AU - Karim, Salman AU - Junaid, Kehinde AU - McGuinness, Bernadette AU - Passmore, Anthony Peter AU - Nilforooshan, Ramin AU - Macharouthu, Ajayverma AU - Donaldson, Andrew AU - Thacker, Simon AU - Russell, Gregor AU - Malik, Naghma AU - Mate, Vandana AU - Knight, Lucy AU - Kshemendran, Sajeev AU - Tan, Tricia AU - Holscher, Christian AU - Harrison, John AU - Brooks, David J. AU - Ballard, Clive AU - Edison, Paul PY - 2021 DA - 2021/02/17 TI - Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer’s subjects? JO - Alzheimer's Research & Therapy SP - 47 VL - 13 IS - 1 AB - Type 2 diabetes is a risk factor for Alzheimer’s disease (AD), and AD brain shows impaired insulin signalling. The role of peripheral insulin resistance on AD aetiopathogenesis in non-diabetic patients is still debated. Here we evaluated the influence of insulin resistance on brain glucose metabolism, grey matter volume and white matter lesions (WMLs) in non-diabetic AD subjects. SN - 1758-9193 UR - https://doi.org/10.1186/s13195-021-00784-w DO - 10.1186/s13195-021-00784-w ID - Femminella2021 ER -