Fig. 3
MR associations between genetic proxies for antihypertensive drug classes and the risk of AD. Genome-wide significantly associated (P < 5 × 10−8) independent (LD R2 < 0.4) SNPs were used as instruments. Bold fonts indicate significant associations. Abbreviations: SNP, single nucleotide polymorphism; OR, odds ratio; CI, confidence interval; AHMs, antihypertensive medications; ARB, angiotensin receptor blockers; BB, β-blockers; CCB, calcium channel blocker; LD, linkage disequilibrium