Fig. 4From: Huanglian Jiedu decoction remodels the periphery microenvironment to inhibit Alzheimer’s disease progression based on the “brain-gut” axis through multiple integrated omicsHLJDD improved the peripheral inflammatory microenvironment in Tg-APP/PS1 mice. a Changes in pro-inflammatory and anti-inflammatory factors (n = 4–5); b Changes in UFAs (n = 6). c Correlation analysis of the CNS UFAs and the peripheral UFAs in each drug treatment group. The colour scale illustrates the magnitude of correlation between the examined indexes on the plot. d PLS-DA plot. All data were analysed by one-way ANOVA with Dunnett-test. All the results are expressed as the mean ± SEM; *P < 0.05, **P < 0.01Back to article page