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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: The use of angiotensin-converting enzyme inhibitors vs. angiotensin receptor blockers and cognitive decline in Alzheimer’s disease: the importance of blood-brain barrier penetration and APOE ε4 carrier status

Fig. 4

Associations between ARB vs. ACE-I use and delayed recall performance over time in APOE ε4 carriers with AD. Left: plot showing full range of outcome scores. Right: plot with reduced y-axis cut-off, to better show differences between ARB and ACE-I groups. Thick lines represent the total estimated association adjusted for covariates; thin lines represent estimated associations adjusted for covariates for each participant. C-ARB: BBB-crossing ARB; C-ACE-I: BBB-crossing ACE-I; NC-ARB: Non-BBB-crossing ARB; NC-ACE-I: Non-BBB-crossing ACE-I

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