Table 1 Demographics, behavioural and cognitive features in P301L MAPT mutation carriers (n = 6) and controls (n = 12)
From: Early anterior cingulate involvement is seen in presymptomatic MAPT P301L mutation carriers
| Mutation carriers, mean (SD) | Controls, mean (SD) | U | p | |
|---|---|---|---|---|
| Age (years) | 44.8 (6.3) | 46.1 (7.2) | 35.50 | 0.98 |
| Sex (male:female) | 1:5 | 6:6 | N/A | 0.32 |
| Estimated years from symptom onset | 12.5 (3.6), range: 7–18 years | 9.5 (9.1), range: − 5.5–29 years | 24.50 | 0.30 |
| Years of education | 16.3 (2.3) | 14.4 (2.2) | 21.50 | 0.17 |
| CDR with NACC FTLD sum of boxes | 0.0 (0.0) | 0.1 (0.2) | 30.00 | 0.53 |
| Mini-Mental State Examination (/30) | 29.8 (0.4) | 29.8 (0.5) | 33.00 | > 0.99 |
| Montreal Cognitive Assessment (/30) | 28.5 (1.8) | 28.3 (1.7) | 33.50 | 0.83 |
| Frontal Assessment Battery (/18) | 17.8 (0.4) | 17.2 (0.9) | 20.00 | 0.16 |