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Table 2 Demographic characteristics of the Aβ+ participants with and without tau-PET

From: Detecting Alzheimer’s disease biomarkers with a brief tablet-based cognitive battery: sensitivity to Aβ and tau PET

 

Tau-PET

(n = 60)

No tau-PET

(n = 37)

t / odds ratio

[95% CI]

P

Age

67.1 (9.2)

70.4 (6.8)

− 2.06 [− 6.61; − 0.12]

.04

Education

16.4 (2.4)

17.6 (2.8)

− 2.01 [−  2.23; − 0.01]

.05

Female

32 (53%)

13 (35%)

1.96 [0.79; 5.04]

.14

Non-Hispanic White

56 (93%)

32 (86%)

1.18 [0.27; 4.75]

.76

MCI

32 (53%)

31 (84%)

4.17 [1.43; 14.06]

.004

Amnestic phenotype

33 (55%)

24 (65%)

0.66 [0.26; 1.66]

.40

CDR-SB

4.3 (2.2)

2.3 (1.7)

2.98 [0.40; 2.01]

.004

Time difference (yrs)

0.2 (0.3)

0.7 (0.9)

− 2.67 [− 0.70; − 0.10]

.01

Favorites z-score

− 2.7 (1.0)

n = 51

− 1.9 (1.1)

n = 36

− 3.17 [− 1.22; − 0.28]

.002

Match z-score

− 4.6 (2.5)

n = 54

− 2.3 (2.3)

n = 37

− 4.28 [− 3.19; − 1.17]

< .001

Line Orientation z-score

− 1.5 (2.6)

n = 56

− 0.5 (2.0)

n = 37

2.15 [− 2.04; − 0.08]

.03

BHS-ECog score

2.6 (0.6)

n = 50

2.3 (0.7)

n = 33

1.58 [− 0.07; 0.58]

.12

  1. Data are presented as mean (standard deviation) for continuous variables and n (% of the total sample) for categorical variables. Time difference represents the years between the BHA completion and PET acquisition presented in absolute values. For Brain Health Assessment measures, the number of participants with complete data is included. P values are based on independent sample t-tests for continuous variables and Fisher’s exact tests for categorical variables between groups with and without tau-PET. The 95% confidence intervals (CI) are reported for mean differences for t-tests and odd ratios for Fisher’s exact tests. BHS-ECog Brain Health Survey Everyday Cognition Scales, CDR-SB Clinical Dementia Rating Scale Sum of Boxes, MCI mild cognitive impairment, PET positron emission tomography, yrs. years