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Table 4 Adjusted odds ratio and 95% confidence intervals for model 1 (ADP versus LRP) and model 2(ADP versus ADP-LRP). Logistic regression model with APOE e4 is the exposure, initial cognitive as outcomes, and pathology as subgroups and age, sex, and education as covariates. Significant results (p < 0.05) are in bold. Model 2: ADP versus ADP-LRP

From: Impact of APOE ε4 genotype on initial cognitive symptoms differs for Alzheimer’s and Lewy body neuropathology

  Amnestic Executive/attention concentration Language Visualspatial
APOEε4 odds in ADP 1.86 (1.3–2.7) 0.88 (0.51–1.54) 0.44 (0.27–0.70) 0.78 (0.36–1.73)
APOEε4 odds in ADP-LRP 2.28 (1.05–4.97) 0.78 (0.24–2.64) 0.28 (0.10–0.77) 1.36 (0.24–8.00)
Age at visit 1.07 (1.06–1.09) 0.95 (0.93–0.96) 0.95 (0.93–0.96) 0.93 (0.91–0.95)
Sex, female 0.44 (0.85–1.37) 0.65 (0.44–0.95) 1.14 (0.85–1.53) 0..94 (0.53–1.64)
Education 0.94 (0.90–1.36) 1.01 (0.95–1.07) 1.1 (1.05–1.16) 1.03 (0.89–1.14)
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