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Table 2 Experimental groups and timeline. Distribution of a total of 96 mice 6- and 12-month-old 5xFAD and age-matched WT mice for each procedural group. All mice were treated orally with SLCP (100 mg/kg BW) every other day for 2 months. IF immunofluorescent, GC Golgi-Cox, FJC fluoro-jade C, m month

From: Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer’s amyloidosis

Groups Group (m) Behavior CV stain GC stain Histochemistry Western blot
WT + vehicle 6 12 (M = 4, F = 2) 3 (M = 2, F = 1) 6 (M = 4, F = 2) 3 (M = 2, F = 1) 3 (M = 2, F = 1)
5xFAD + vehicle 6 12 (M = 4, F = 2) 3 (M = 1, F = 2) 3 (M = 1, F = 2) 3 (M = 2, F = 1) 3 (M = 2, F = 1)
5xFAD + SLCP 6 12 (M = 2, F = 4) 3 (M = 2, F = 1) 3 (M = 2, F = 1) 3 (M = 1, F = 2) 3 (F = 3)
WT + SLCP 6 12 (M = 4) 3 (M = 1, F = 2) 6 (M = 3, F = 3) 3 (M = 1, F = 2) 3 (M = 2, F = 1)
WT + vehicle 12 11 (M = 6, F = 5) 3 (M = 2, F = 1) 3 (M = 2, F = 1) 3 (M = 2, F = 1) 3 (M = 1, F = 2)
5xFAD + vehicle 12 10 (M = 6, F = 4) 3 (M = 2, F = 1) 6 (M = 2, F = 4) 3 (M = 2, F = 1) 3 (M = 2, F = 1)
5xFAD + SLCP 12 11 (M = 7, F = 4) 3 (M = 1, F = 2) 3 (M = 1, F = 2) 3 (M = 1, F = 2) 3 (M = 1, F = 2)
WT + vehicle 12 10 ((M = 6, F = 4) 3 (M = 2, F = 1) 6 (M = 2, F = 1) 3 (M = 2, F = 1) 3 (M = 1, F = 2)