Table 3 mGluR5 binding ([¹⁸F]FPEB BP_ND) in brain regions of interest

 Hippocampus

1.78 (0.61)

1.30 (0.33)

0.011*

2.69 (0.88)

2.19 (0.45)

0.0499*

 Composite association cortex

2.38 (0.76)

2.04 (0.29)

0.111

4.39 (1.30)

3.99 (0.47)

0.258

 Prefrontal cortex

2.43 (0.78)

2.15 (0.29)

0.197

4.48 (1.34)

4.10 (0.49)

0.310

 Entorhinal cortex

1.99 (0.72)

1.52 (0.43)

0.034*

3.18 (1.18)

2.69 (0.54)

0.144

 Parahippocampal gyrus

1.96 (0.69)

1.58 (0.33)

0.052

3.26 (1.13)

2.86 (0.44)

0.199

 Lateral temporal cortex

2.43 (0.81)

2.03 (0.31)

0.075

4.24 (1.34)

3.78 (0.45)

0.204

 Lateral parietal cortex

2.32 (0.72)

1.97 (0.31)

0.091

4.44 (1.26)

4.01 (0.52)

0.211

 Posterior cingulum

1.65 (0.64)

1.42 (0.30)

0.219

3.23 (1.05)

3.01 (0.45)

0.448

 Precuneus

2.15 (0.66)

1.82 (0.27)

0.079

4.08 (1.16)

3.71 (0.47)

0.249

 Occipital cortex

2.02 (0.59)

1.77 (0.25)

0.120

3.82 (1.03)

3.57 (0.41)

0.388

 Caudate

2.17 (0.86)

1.98 (0.42)

0.439

3.41 (1.26)

3.14 (0.46)

0.427

 Putamen

2.79 (0.91)

2.57 (0.35)

0.381

4.44 (1.37)

4.19 (0.64)

0.514

 Pallidum

0.96 (0.41)

0.81 (0.42)

0.312

2.50 (1.18)

2.30 (0.83)

0.599

 Thalamus

1.38 (0.61)

1.12 (0.27)

0.118

2.40 (0.91)

2.04 (0.41)

0.162