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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Alzheimer’s cerebrospinal biomarkers from Lumipulse fully automated immunoassay: concordance with amyloid-beta PET and manual immunoassay in Koreans

Fig. 1

Summarized flow chart of study population. Among 271 subjects with amyloid PET imaging, in the participants with amyloid PET imaging but without CSF (n = 143), we yielded SUVR cutoff values for amyloid PET positivity with best discrimination of AD from the CN group, and then, the SUVR cutoffs were used to determine the cutoff values for CSF biomarkers following Youden’s index to differentiate participants with amyloid PET positivity (n = 128). Finally, we evaluated the predictive performances of CSF AD biomarkers in 139 subjects who provided CSF samples, using the amyloid PET-based cutoff values of CSF AD biomarkers

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