Subjects (N = 2603) | Events (N = 928) | Deaths (N = 45) | Unadjusted RR | Unadj. p value | Adjusted RR | Adj. p value | |
---|---|---|---|---|---|---|---|
Partner typea | 0.595 | 0.53 | |||||
Spouse | 720 | 268 | 13 | 1 | – | 1 | – |
Adult child | 171 | 69 | 6 | 1.13 (0.86, 1.48) | 0.374 | 0.81 (0.49, 1.36) | 0.427 |
Other | 80 | 32 | 0 | 1.12 (0.78, 1.62) | 0.532 | 1.06 (0.66, 1.72) | 0.802 |
Participant age (per 10 years) | 971 | 369 | 19 | 1.47 (1.30, 1.66) | < .001 | 1.47 (1.23, 1.75) | < .001 |
Education (years) | 971 | 369 | 19 | 0.95 (0.92, 0.98) | 0.001 | 0.97 (0.93, 1.00) | 0.034 |
Partner age (per 10 years) | 971 | 369 | 19 | 1.12 (1.02, 1.23) | 0.021 | 0.97 (0.82, 1.14) | 0.699 |
Baseline test scores | |||||||
Mini-Mental State Exam | 971 | 369 | 19 | 0.94 (0.91, 0.97) | < .001 | 0.94 (0.91, 0.97) | < .001 |
Hachinski Score | 971 | 369 | 19 | 1.12 (1.00, 1.26) | 0.049 | 1.04 (0.92, 1.19) | 0.513 |
Geriatric Depression Scale | 971 | 369 | 19 | 1.08 (1.01, 1.15) | 0.035 | 1.08 (1.01, 1.16) | 0.031 |
Participant sex | |||||||
Female | 504 | 188 | 8 | 1 | – | 1 | – |
Male | 467 | 181 | 11 | 1.02 (0.83, 1.26) | 0.821 | 1.02 (0.73, 1.42) | 0.903 |
Partner sex | |||||||
Female | 600 | 239 | 13 | 1 | – | 1 | – |
Male | 371 | 130 | 6 | 0.86 (0.69, 1.06) | 0.162 | 0.88 (0.64, 1.23) | 0.469 |
Partner employed | |||||||
No | 649 | 270 | 13 | 1 | – | 1 | – |
Yes | 322 | 99 | 6 | 0.69 (0.54, 0.86) | 0.001 | 0.75 (0.57, 0.99) | 0.046 |
APOE carrier | |||||||
No | 318 | 127 | 7 | 1 | – | 1 | – |
Yes | 653 | 242 | 12 | 0.88 (0.71, 1.10) | 0.263 | 0.96 (0.76, 1.22) | 0.76 |
Race/ethnicity | |||||||
White | 922 | 346 | 16 | 1 | – | 1 | – |
Asian | 13 | 6 | 0 | 1.13 (0.54, 2.38) | 0.741 | 1.15 (0.50, 2.63) | 0.743 |
Hispanic | 16 | 8 | 3 | 1.30 (0.65, 2.60) | 0.452 | 1.07 (0.52, 2.19) | 0.861 |
African American/Black | 20 | 9 | 0 | 1.43 (0.70, 2.93) | 0.325 | 1.18 (0.52, 2.68) | 0.69 |