Table 1 Sample characteristics

Age, years

69.9 (7.8)

70.8 (6.4)

67.1 (7.4)

73.3 (7.2)

68 (10.2)

.002^a,d,f

Sex, n females (%)

86 (55.5)

24 (47.1)

17 (60.7)

29 (56.9)

16 (64)

.466

Education, years

11.9 (3.7)

12.2 (3.8)

13.4 (3.5)

11 (3.6)

11.6 (3.3)

.045^d

ApoE, allele 4 carriers (%)^#

49 (33.6)

10 (19.6)

3 (11.1)

21 (44.7)

15 (71.4)

< .001^b,c,d,e,f

MMSE, /30^#

26.7 (3.8)

28.7 (1.2)

29 (1.1)

26.7 (1.9)

20 (4.5)

< .001^b,c,d,e,f

Systolic blood pressure, mmHg^#

142.4 (21.5)

145.2 (20.8)

135.3 (22.6)

145 (23.4)

138.4 (16.2)

.171

Diastolic blood pressure, mmHg^#

80.1 (12.4)

82.6 (12.4)

78.5 (12.4)

79.1 (13.3)

78.7 (10.2)

.401

AV45-PET SUVR in AD meta-signature^#

1.28 (.25)

1.13 (.13)

1.14 (.14)

1.36 (.25)

1.53 (.25)

< .001^b,c,d,e,f

FDG-PET SUVR in AD meta-signature^#

1.38 (.13)

1.45 (.08)

1.47 (.1)

1.34 (.09)

1.24 (.16)

< .001^b,c,d,e,f

GMV in AD meta-signature, mL

7.81 (1.03)

8.29 (.68)

8.31 (.68)

7.32 (1.07)

7.24 (1.15)

< .001^b,c,d,e

WMH volume, mL

10.14 (11.24)

6.34 (6.9)

8.21 (9.65)

12.98 (15.07)

14.27 (13.52)

.005^b,c,e