Table 1 Demographic characteristics of subjects included
From: An MRI-based strategy for differentiation of frontotemporal dementia and Alzheimer’s disease
NACC | FTD (n = 47) | AD (n = 47) | NC (n = 47) | p value |
Age (years), mean (SD) | 64.55 (10.15) | 64.55 (10.28) | 64.57 (10.13) | > 0.999 |
Education (years), mean (SD) | 15.45 (2.98) | 15.62 (2.78) | 15.68 (2.86) | 0.920 |
Gender, male (n (%)) | 25 (53.2) | 25 (53.2) | 25 (53.2) | > 0.999 |
Race, White (n (%)) | 47 (100.0) | 47 (100.0) | 47 (100.0) | > 0.999 |
ICV (mL), mean (SD) | 1472.14 (155.82) | 1526.37 (170.79) | 1505.12 (145.51) | 0.247 |
Global CDR^ | > 0.999 | |||
0.0 = no impairment (n (%)) | 6 (12.8) | 6 (12.8) | 47 (100.0) | – |
0.5 = questionable impairment (n (%)) | 21 (44.7) | 21 (44.7) | – | – |
1.0 = mild impairment (n (%)) | 17 (36.2) | 17 (36.2) | – | – |
2.0 = moderate impairment (n (%)) | 3 (6.4) | 3 (8.5) | – | – |
ADNI + FTLDNI | FTD (n = 50) | AD (n = 50) | – | p value |
Age (years), mean (SD) | 64.64 (7.09) | 64.22 (7.58) | – | 0.484 |
Education (years), mean (SD) | 15.98 (3.57) | 16.02 (2.56) | – | 0.241 |
Gender, male (n (%)) | 27 (54.0) | 23 (46.0) | – | 0.548 |
Race, White (n (%)) | 45 (90.0) | 46 (92.0) | – | 0.727 |
ICV (mL), mean (SD) | 1521.82 (131.45) | 1456.48 (158.80) | 0.070 | |
Global CDR^ | – | 0.002 | ||
0.0 = no impairment (n (%)) | 3 (6.0) | 0 (0.0) | – | – |
0.5 = questionable impairment (n (%)) | 24 (48.0) | 20 (40.0) | – | – |
1.0 = mild impairment (n (%)) | 16 (32.0) | 30 (60.0) | – | – |
2.0 = moderate impairment (n (%)) | 7 (14.0) | 0 (0.0) | – | – |