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Table 1 Demographic characteristics of study subjects in ADNI

From: Associations of Alzheimer’s disease risk variants with gene expression, amyloidosis, tauopathy, and neurodegeneration

Characteristics NC (N = 339) MCI (N = 639) AD (N = 205)
Age (mean years ± SD) 75.15 ± 5.35 73.44 ± 7.52 75.53 ± 7.81
Gender (n (%))   
 Male 177 (52.21) 389 (60.88) 117 (57.07)
 Female 162 (47.79) 250 (39.12) 88 (42.93)
Education (mean years ± SD) 16.30 ± 2.68 15.89 ± 2.84 15.03 ± 2.96
APOE status (n (%))
APOE ε2/ε2,ε2/ε3,ε3/ε3 247 (72.86) 325 (50.86) 66 (32.20)
APOE ε2/ε4,ε3/ε4 83 (24.48) 250 (39.12) 101 (49.27)
APOE ε4/ε4 9 (2.65) 64 (10.02) 38 (18.54)
MMSE (means ± SD) 29.07 ± 1.12 27.60 ± 1.78 23.29 ± 2.03
  1. Abbreviations: AD Alzheimer’s disease, ADNI Alzheimer’s Disease Neuroimaging Initiative, MCI mild cognitive impairment, MMSE Mini-Mental State Exam scores, N number, NC normal cognition, SD standard deviation